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The DRP-1 fission protein inhibitor, Mdivi-1, reversibly reduces neurite growth rate and lamellar, but not filopodial protrusion. A. Neurite growth rate and B. lamellar protrusion (white circles) were reversibly and repeatedly inhibited by Mdivi-1. Filopodial protrusion frequency (black squares) was unchanged with the initial Mdivi-1 perfusion, but increased briefly after washout [43]. C. Summary of acute effects of inhibiting DRP-1 in already established axons.
