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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Gynecol Oncol. 2013 Nov 15;132(1):194–202. doi: 10.1016/j.ygyno.2013.11.010

Figure 4.

Figure 4

Intratumoral MV-NIS or VSV-hIFNβ treatment of endometrial xenografts derived from HEC1A (A–D) or AN3CA (E–H) cells. Subcutaneous xenografts were established in the right flank of athymic nude mice. Once tumors formed, the mice were assigned randomly to a single IT injection of saline, MV-NIS, or VSV-hIFNβ (1×107 TCID50). A–C and E–G, Individual tumor volumes for the duration of the study for each study group. D and H, Survival of each group was plotted on a Kaplan-Meier survival curve. P values were determined by the log-rank (Mantel-Cox) method and shown as tables underneath the survival curve of each tumor model. P<.05 was considered significant. Study was ended at day 100 after virus injection. Five mice were included in each group, except the AN3CA saline group, which comprised 4 mice.