. Author manuscript; available in PMC: 2015 Feb 1.

Published in final edited form as: J Ind Microbiol Biotechnol. 2013 Nov 19;41(2):451–459. doi: 10.1007/s10295-013-1373-4

Table 1.

Summary of published work using microbial proteomics to interrogate the expression of genes and gene clusters encoding enzymes responsible for the biosynthesis of secondary metabolites and natural products.

Organism(s) Studied	Instrumentation	Biosynthetic Pathways Studied	Reference
Bacillus subtilis, Streptomyces sp.	LTQ-FTICR (12T)	gramicidin S, kurstakins, zwittermicins	2
Bacillus subtilis	LTQ-Ion Trap	surfactin, bacillibactin, bacillaene, plipastatin	17
Bacillus subtilis	LTQ-Ion Trap	surfactin, bacillibactin, plipastatin	16
Streptomyces sp.	LTQ-FTICR (7T)	flavopeptin	6
Bacillus subtilis	FTICR	nikkomycin, pyoluteorin, prodigiosin, gramicidin, mycosubtilin, enterobactin	11
Streptococcus agalactiae	LTQ	putative pks	18
Streptomyces sp.	LTQ-Orbitrap	gobichelin	8
Actinobacteria	LTQ-FTICR (7T)	foroxymithine, antibiotic S213 L, actinomycin, etc.	7
Bacillus sp.	LTQ-FTICR (7T)	koranimine	12
Frankia sp.	LTQ	25+ individual pathways	23