Effect of nicotine replacement therapy (NRT) on smoking relapse differs in fast vs. slow nicotine metabolizers defined by CYP2A6 genotype a
There is a significant interaction between NRT and CYP2A6 (interaction effect size=1.82, 95%CI=1.07-3.10, p=0.028).
NRT: Nicotine Replacement Therapy
a Time to relapse over 90 days. b The group with NRT includes all treatment arms with NRT (the NRT arms and the arm receiving both NRT and bupropion. c The group without NRT includes all treatment arms without NRT (the placebo arm and the arm receiving bupropion alone).