Table 1.

SNP metrics and genotype counts. HWpval: Hardy Weinberg P value; %Geno: % genotyped; Maj/Min Major/minor alleles; MAF: minor allele frequency; Macular pigment optical density area (MPOD_Area); serum zeaxanthin (serum Z); serum lutein (serum L); Unadj: unadjusted P value; Adj: Adjusted P value (for age, sex, smoking status, body mass index, high density lipoprotein cholesterol, low density lipoprotein cholesterol, triglycerides, dietary L and Z); Perm: P value following permutation test (n=100,000).

					Maj/Min Alleles		MPOD Area			Serum Z			Serum L
SNP	Position	HWpval	%Geno	Genotypes		MAF	Unadj	Adj	Perm	Unadj	Adj	Perm	Unadj	Adj	Perm
rs838873	125257551	0.456	99.7	7/67/226	T:C	0.138	0.299	0.381	1	0.371	0.237	0.999	0.016	0.013	0.312
rs838882	125261813	0.543	99.7	17/119/164	T:C	0.255	0.749	0.656	1	0.558	0.521	1	0.282	0.534	1
rs838883	125261839	0.581	100.0	1/30/270	C:T	0.055	0.866	0.882	1	0.662	0.491	1	0.973	0.712	1
rs838887	125265973	0.690	99.7	32/127/141	C:G	0.314	0.461	0.645	1	0.272	0.568	1	0.734	0.966	1
rs838891	125268432	0.356	99.7	35/124/141	A:G	0.319	0.729	0.999	1	0.403	0.838	1	0.887	0.562	1
rs838892	125269323	0.894	99.3	30/128/141	G:T	0.309	0.746	0.960	1	0.467	0.887	1	0.966	0.589	1
rs838896	125269799	0.692	96.3	30/132/128	G:C	0.324	0.652	0.387	1	0.159	0.579	1	0.960	0.337	1
rs838865	125273767	1.000	95.3	0/19/268	G:A	0.033	0.168	0.259	0.999	0.675	0.361	1	0.118	0.354	1
rs1031605	125276969	0.247	80.7	9/62/172	C:T	0.158	0.553	0.538	1	0.268	0.134	0.971	0.520	0.458	1
rs12819677	125283521	0.348	97.0	63/155/74	T:C	0.480	0.826	0.657	1	0.989	0.648	1	0.736	0.935	1
rs5888	125284748	0.293	99.3	54/157/88	C:T	0.440	0.871	0.771	1	0.899	0.805	1	0.975	0.809	1
rs838909	125287648	0.356	99.0	64/157/77	C:T	0.477	0.842	0.737	1	0.880	0.643	1	0.961	0.858	1
rs3782287	125289265	0.416	98.7	64/156/77	A:G	0.477	0.842	0.735	1	0.885	0.638	1	0.957	0.852	1
rs865716	125290856	0.293	98.7	57/157/83	A:T	0.455	0.754	0.704	1	0.871	0.982	1	0.994	0.865	1
rs838905	125291006	1.000	97.3	0/14/279	T:C	0.023	0.931	0.841	1	0.201	0.028	0.549	0.247	0.756	1
rs11057820	125296964	0.249	99.7	62/160/78	T:C	0.470	0.010	0.008	0.225	0.867	0.785	1	0.119	0.023	0.478
rs4765615	125299830	0.563	99.7	63/155/82	T:C	0.465	0.105	0.092	0.915	0.617	0.307	1	0.146	0.033	0.606
rs745529	125300472	0.783	99.3	25/127/147	G:T	0.291	0.101	0.117	0.956	0.312	0.733	1	0.533	0.944	1
rs1902569	125304004	1.000	99.3	46/143/110	G:A	0.383	0.196	0.244	1	0.868	0.578	1	0.706	0.337	1
rs11057830	125307053	1.000	99.7	4/67/229	G:A	0.128	0.569	0.373	1	0.319	0.341	1	0.003	0.002	0.062
rs10846744	125312425	1.000	85.4	4/55/198	G:C	0.125	0.389	0.306	1	0.639	0.831	1	0.011	0.011	0.269
rs10846745	125312612	0.214	70.4	49/96/67	C:G	0.464	0.047	0.039	0.650	0.048	0.022	0.464	0.004	2×10−4	0.010
rs11608336	125313426	0.908	99.3	64/151/84	C:T	0.473	0.075	0.078	0.874	0.216	0.123	0.962	0.010	0.001	0.041
rs7135223	125314414	0.720	99.7	47/148/105	G:A	0.392	0.386	0.562	1	0.674	0.563	1	0.720	0.433	1
rs11057841	125316743	0.599	99.0	6/64/228	C:T	0.130	0.730	0.495	1	0.228	0.239	0.999	2×10−4	2×10−4	0.006
rs12581963	125317125	0.132	99.3	3/34/262	G:A	0.069	0.927	0.964	1	0.565	0.620	1	0.001	0.003	0.098
rs12580803	125317247	0.010	81.4	7/38/200	A:G	0.111	0.043	0.049	0.732	0.303	0.689	1	0.719	0.879	1
rs10773107	125317391	0.410	96.0	67/137/85	C:A	0.469	0.376	0.269	1	0.580	0.385	1	0.163	0.056	0.780
rs10744182	125317582	0.724	99.7	58/144/98	T:C	0.429	0.806	0.765	1	0.846	0.690	1	0.369	0.298	1
rs4765180	125318772	0.220	95.7	52/128/108	C:T	0.412	0.933	0.962	1	0.583	0.611	1	0.149	0.111	0.947
rs10846751	125319771	0.500	99.7	31/123/146	G:A	0.312	0.571	0.574	1	0.687	0.711	1	0.584	0.557	1
rs4765622	125320828	1.000	100.0	67/150/84	A:G	0.479	0.661	0.671	1	0.721	0.731	1	0.155	0.047	0.725
rs4765623	125320850	0.496	98.7	31/121/145	C:T	0.313	0.665	0.654	1	0.668	0.735	1	0.614	0.603	1
rs10846753	125321461	0.697	99.7	11/87/202	T:G	0.184	0.285	0.204	0.996	0.358	0.347	1	0.493	0.127	0.966
rs10773109	125322995	0.716	99.7	44/147/109	C:G	0.401	0.707	0.568	1	0.065	0.047	0.724	0.026	0.001	0.032
rs12582221	125323240	1.000	98.0	68/148/79	G:A	0.469	0.944	0.935	1	0.166	0.200	0.996	0.035	0.017	0.397
rs7306660	125327384	0.243	99.7	28/142/130	G:A	0.334	0.162	0.096	0.922	0.795	0.683	1	0.127	0.228	0.998
rs3924313	125328375	0.496	99.0	25/133/140	G:A	0.311	0.612	0.432	1	0.531	0.469	1	0.187	0.324	1
rs11057851	125328779	1.000	100.0	4/64/233	G:A	0.123	0.108	0.186	0.994	0.050	0.037	0.643	0.680	0.605	1
rs11057852	125328826	1.000	99.0	0/21/277	C:T	0.038	0.476	0.535	1	0.357	0.568	1	0.015	0.120	0.959
rs11057853	125329313	1.000	99.3	54/146/99	T:C	0.434	0.027	0.031	0.572	0.374	0.295	1	0.643	0.647	1
rs7954697	125335253	0.0004	61.5	58/68/59	A:C	0.488	0.156	0.137	0.974	0.159	0.129	0.967	0.743	0.600	1
rs4765181	125339228	0.146	96.3	54/128/108	C:A	0.399	0.085	0.079	0.879	0.046	0.093	0.916	0.039	0.039	0.659
rs11615630	125341870	0.178	99.3	49/130/120	C:T	0.389	0.588	0.472	1	0.924	0.607	1	0.935	0.876	1
rs7139401	125345448	0.165	73.8	1/11/210	G:A	0.032	0.697	0.925	1	0.354	0.380	1	0.147	0.164	0.987
rs4379922	125351116	0.265	99.0	46/130/122	T:C	0.380	0.296	0.221	0.998	0.698	0.566	1	0.656	0.889	1
rs6488950	125354103	0.146	79.4	0/49/190	C:T	0.098	0.250	0.266	1	0.517	0.247	0.999	0.705	0.231	0.998