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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: J Immunol. 2013 Dec 13;192(3):859–866. doi: 10.4049/jimmunol.1301062

Figure 1.

Figure 1

EGFR signaling protects from skin barrier function impairment following cutaneous allergen exposure. A. Overview of the acute AD sensitization protocol. Mice were exposed to A. fumigatus (ASP) or saline (SAL) patch 3 times as indicated and TEWL was assessed 24 hours after the last patch was removed in B. BALB/c mice treated with EGF as indicated; C. Waved-2 (WD2) mice and C57Bl/6 wild type mice; D. BALB/c mice treated with erlotinib as indicated. n=4–8 mice/group *P<0.05, ***P<0.001. Each experiment was performed a minimum of 3 times.