Table 2.
Recipient Functional Status alone |
Recipient Age alone |
Recipient Age and Functional Status |
Full Model: All Recipient and Donor Attributes |
|||||
---|---|---|---|---|---|---|---|---|
HR (CI) | p- value |
HR (CI) | p- value |
HR (CI) | p- value |
HR (CI) | p-value | |
FUNCTIONAL STATUS | ||||||||
Highest | Reference | Reference | Reference | |||||
Near-highest | 1.28 (1.12, 1.47) | <0.001 | 1.15 (1.01, 1.33) | 0.04 | 1.09 (0.94, 1.77) | 0.25 | ||
Near-lowest | 1.54 (1.36, 1.76) | <0.001 | 1.36 (1.20, 1.55) | <0.001 | 1.28 (1.12, 1.46) | <0.001 | ||
Lowest | 2.30 (2.03, 2.61) | <0.001 | 1.88 (1.66, 2.14) | <0.001 | 1.66 (1.45, 1.89) | <0.001 | ||
AGE | ||||||||
<35 years | Reference | Reference | Reference | |||||
≥35 & <45 years | 1.54 (1.17, 2.04) | 0.002 | 1.49 (1.13, 1.96) | 0.005 | 1.25 (0.94, 1.67) | <0.001 | ||
≥45 & <55 years | 2.47 (1.89, 3.23) | <0.001 | 2.26 (1.73, 2.96) | <0.001 | 1.75 (1.32, 2.32) | <0.001 | ||
≥55 & <65 years | 3.84 (2.95, 5.00) | <0.001 | 3.40 (2.61, 4.43) | <0.001 | 2.55 (1.92, 3.38) | <0.001 | ||
≥65 years | 5.71 (4.37, 7.47) | <0.001 | 5.10 (3.90, 6.68) | <0.001 | 3.79 (2.84, 5.05) | <0.001 |
Full model also adjusted for: recipient attributes of race, sex, diabetes status, prior solid organ transplant, dialysis time, panel reactive antibody, hepatitis C serostatus, glomerulonephritis, polycystic kidney disease, congenital/reflex kidney disease, hypertensive kidney disease, and cytomegalovirus status; donor attributes of type (live, deceased versus extended criteria deceased), age, race (black versus other), and cytomegalovirus status; and allograft attributes of human leukocyte antigen mismatch.