Table 4.
NY-ESO-1 expression in malignant melanoma lesions according to morphology
| Morphology | NY-ESO-1 expression
|
|||
|---|---|---|---|---|
| Primary (%) | Metastatic (%) | Total (%) | ||
| Melanoma | ||||
| Epithelioid | 13 (65.0) | 172 (83.5) | 185 (83.3) | |
| With anaplastic features | 1 (50) | 5 (2.4) | ||
| Spindle | 1 (20.0) | 22 (10.7) | 23 (10.4) | |
| With desmoplastic features | 0 | 3 (1.5) | ||
| Mixed | 1 (6.25) | 8 (3.9) | 9 (4.1) | |
| Balloon | 1 (6.25) | 4 (1.9) | 5 (2.3) | |
| Total | 16 | 206 | 222 | |
| Metastatic melanoma | Positive (%) | Negative (%) | Total (%) | |
| Epithelioid | 56 (32.6) | 116 (67.4) | 172 | |
| With anaplastic features | 2 (1.1) | 3 | ||
| Spindle | 2 (9.1) | 20 (90.9) | 22 | |
| With desmoplastic features | 2 (9.1) | 1 | ||
| Mixed | 0 | 8 (100) | 8 | |
| Balloon | 0 | 4 (100) | 4 | |
| Total | 58 | 148 | 206 | |
| Metastatic melanoma excluding multiple specimens from same patient | ||||
| Epithelioid | 37 (30.8) | 83 (69.2) | 120 | |
| With anaplastic features | 2 (1.7) | 3 | ||
| Spindle | 2 (10.5) | 17 (89.5) | 19 | |
| With desmoplastic features | 2 (10.5) | 1 | ||
| Mixed | 0 | 7 (100) | 7 | |
| Balloon | 0 | 2 (100) | 2 | |
| Total | 39 | 109 | 148 | |
NOTE. Mixed is epithelioid and spindle cell subtypes.