Table 1.
Clinical characteristics of non-survivors and survivors.
Non-survivors (n = 40) | Survivors (n = 277) | p value | |
---|---|---|---|
Median age in years (IQR) | 1.3 (0.2 – 4.5) | 2.9 (1.1 – 6.7) | 0.007 |
Number of males (%) | 26 (65) | 166 (59) | 0.225 |
Median PRISM score | 28 (17 – 37) | 12 (7 – 18) | <0.001 |
Number with renal failure (%) | 11 (27) | 23 (8) | <0.001 |
Median fluid intake/kg in first 24 hours | 178 (134 – 227) | 138 (100 – 186) | 0.003 |
%Positive fluid balance in first 24 hours | 10.6 (3.8 – 15.7) | 4.5 (1.3 – 9.8) | <0.001 |
Cumulative %positive fluid balance | 19.5 (10.5 – 40.1) | 6.5 (−1.3 – 14.6) | <0.001 |
PERSEVERE probability of mortality | 0.472 (0.222 – 0.472) | 0.011 (0.011 – 0.182) | <0.001 |
# of subjects < 28 days of age (%) | 9 (23) | 22 (8) | 0.004 |
# with gram positive infection (%) | 10 (25) | 66 (24) | 0.871 |
# with gram negative infection (%) | 8 (20) | 54 (19) | 0.940 |
# with viral infection (%) | 4 (10) | 15 (5) | 0.253 |
# with fungal infection (%) | 0 (0) | 2 (1) | 0.590 |
# with mixed infection (%) | 1 (3) | 10 (4) | 0.720 |
# with no organism identified (%) | 17 (43) | 130 (47) | 0.599 |