Table 3.
Genotype distribution and allele frequency of FSHR polymorphism
| Genotype | Cases (n = 215) | Controls (n = 205) | p value |
|---|---|---|---|
| A307T(rs6165) | |||
| Thr/Thr(AA) | 93 (43.3 %) | 91 (44.4 %) | 0.133 |
| Ala/Thr(AG) | 95 (44.2 %) | 100 (48.8 %) | |
| Ala/Ala(GG) | 27 (12.6 %) | 14 (6.8 %) | |
| H-W test | 0.721 | 0.052 | |
| Allele frequency | |||
| Ala(G) | 149 (15.3 %) | 128 (31.5 %) | 0.29 |
| Thr(A) | 281 (65.2 %) | 282 (69.3 %) | |
| N680S(rs6166) | |||
| Asn/Asn(AA) | 93 (43.3 %) | 94 (45.9 %) | 0.069 |
| Ser/Asn(AG) | 94 (43.7 %) | 98 (47.8 %) | |
| Ser/Ser(GG) | 28 (13.0 %) | 13 (6.3 %) | |
| H-W test | 0.581 | 0.057 | |
| Allele frequency | |||
| Asn(A) | 280 (69.8 %) | 286 (69.8 %) | 0.152 |
| Ser(G) | 150 (30.2 %) | 124 (30.2 %) | |
p values from chi-squared test
H–W test Hardy–Weinberg equilibrium test