Table 2. Within-group contrasts.
Within-groups significant clusters (p (uncorrected) < 0.005, minimum cluster = 10 voxels), in each of the three contrasts examined: own interest – visual baseline, others’ interests – visual baseline, and own interest – others’ interests. Clusters that survived correction using 5000 iterations of a Monte Carlo simulation are shown in BOLD and denoted with an
Own-Baseline |
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---|---|---|---|---|---|---|---|
Group | Region | x | y | z | K | Zmax | p(uncorr) |
ASD | R amygdala | 23 | −3 | −20 | 93* | 4.63 | .000 |
L amygdala | −18 | −3 | −20 | 63* | 4.15 | .000 | |
R subgenual ACC | 8 | 15 | −15 | 19 | 3.42 | .000 | |
L subgenual ACC | −3 | 10 | −10 | 11 | 3.19 | .001 | |
L caudate (head) | −13 | 25 | −8 | 16 | 3.15 | .001 | |
TD | R amygdala | 23 | −5 | −18 | 48* | 4.26 | .000 |
L amygdala | −20 | −5 | −18 | 36* | 3.64 | .000 | |
R subgenual ACC | 5 | 13 | −13 | 28 | 4.45 | .000 | |
L subgenual ACC | −5 | 8 | −13 | 25 | 4.47 | .000 | |
R IFG | 33 | 30 | −8 | 16 | 3.27 | .001 | |
L IFG | −38 | 33 | −20 | 20 | 3.71 | .000 | |
R posterior insula | 33 | 23 | 20 | 11 | 3.04 | .001 | |
L MFG | −8 | 30 | −15 | 55* | 4.05 | .000 |
Other-Baseline |
|||||||
---|---|---|---|---|---|---|---|
Group | Region | x | y | z | K | Zmax | p(uncorr) |
ASD | R amygdala | −25 | −3 | −23 | 50* | 4.44 | .000 |
L amygdala | 23 | −3 | −20 | 22 | 3.73 | .000 | |
TD | R amygdala | 25 | −5 | 18 | 28 | 3.63 | .000 |
L amygdala | −20 | −5 | −18 | 36* | 4.00 | .000 | |
L subgenual ACC | −8 | 25 | −15 | 10 | 3.41 | .000 | |
L OFC (extending through IFG and anterior insula) | −40 | 33 | −20 | 115* | 3.99 | .000 | |
R IFG | 35 | 33 | −5 | 12 | 3.36 | .000 | |
R Nac | 8 | 13 | −15 | 11 | 4.19 | .000 | |
L Nac | −8 | 10 | −15 | 21 | 3.13 | .001 |
Own-Other |
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---|---|---|---|---|---|---|---|
Group | Region | x | y | z | K | Zmax | p(uncorr) |
ASD | R IFG | 23 | 28 | −15 | 13 | 3.14 | .001 |
L IFG | −35 | 30 | −5 | 11 | 3.78 | .000 | |
TD | ACC | −5 | 3 | 30 | 16 | 3.24 | .001 |
ACC: anterior cingulate cortex; IFG: inferior frontal gyrus; MFG: medial frontal gyrus; OFC: orbitofrontal cortex; Nac: nucleus accumbens.