Table 5.
Scenario | ||||||
---|---|---|---|---|---|---|
8 | 9 | 10 | 11 | 12 | 13 | |
Probability of selecting an acceptable combination as MTD | 0.63 | 0.77 | 0.68 | 0.65 | 0.66 | 0.43 |
Probability of selecting no combination as MTD | 0.00 | 0.00 | 0.02 | 0.01 | 0.00 | 0.00 |
Mean number of patients enrolled | 25.9 | 25.4 | 23.3 | 24.5 | 25.4 | 25.8 |
Observed incidence of toxicity | 0.18 | 0.27 | 0.34 | 0.29 | 0.32 | 0.30 |