Fig. 1.

Change in body weight and average daily food intake in control and tumor-bearing rats (TBL, lower tertile; TBU, upper tertile) following chronic saline or Exendin-4 treatment. a Terminal change in body weight, minus tumor weight, was significantly lower in saline-treated TBL and TBU rats, as compared to controls (p < 0.05). In contrast, terminal change in body weight was significantly lower in Exendin-4 treated TBU rats, as compared to both control and TBL rats. No significant differences were found between control and TBL Exendin-4-treated rats. b Food intake was significantly lower in Exendin-4-treated rats, as compared to saline-treated rats, but no differences were observed based on tumor status. *p < 0.05 compared to control, #p < 0.05 compared to TBL