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. Author manuscript; available in PMC: 2015 Feb 20.
Published in final edited form as: Stat Med. 2013 Sep 6;33(4):675–692. doi: 10.1002/sim.5966

Table 4.

Simulation results for Poisson regression: E(Y|X) = exp(β0 + β1X), where X = L + Ub; W = L + Uc; β = (0.5, ln(2))′; M = 1 − 2L + V; Q = −1 + 2X + ; θ is the proportion of the calibration data; L ~ N(0.5,1); Ub ~ N(0,σb2) is the Berkson error; Uc ~ N(0,σc2) is the classical error; V ~ N(0,1); ~ N(0,1); n = 500; Naive, “naive” regression replacing X by W;RC1, Regression calibration approach replacing X by its conditional expectation given W; RC2, Regression calibration approach replacing X by its conditional expectation given W and Q, M in the calibration sample; SIMEX, simulation extrapolation procedure; EEE, Expected estimating equation method.

σc2 = 0.3
σc2 = 0.5
θ σb2 β Naive RC1 RC2 SIMEX EEE Naive RC1 RC2 SIMEX EEE
0.5 0.2 β 0 Bias 0.183 0.103 0.075 0.010 0.002 0.242 0.124 0.086 0.022 −0.001
SD 0.048 0.054 0.053 0.058 0.056 0.046 0.053 0.053 0.058 0.053
ASE 0.046 0.052 0.051 0.055 0.053 0.046 0.057 0.056 0.059 0.057
CP 0.048 0.481 0.670 0.927 0.935 0.005 0.420 0.686 0.917 0.962
β 1 Bias −0.159 0.000 −0.006 −0.012 −0.001 −0.230 0.007 −0.004 −0.030 0.004
SD 0.037 0.057 0.051 0.045 0.048 0.035 0.066 0.056 0.047 0.051
ASE 0.033 0.055 0.049 0.043 0.045 0.032 0.065 0.056 0.046 0.051
CP 0.023 0.942 0.929 0.917 0.932 0.003 0.957 0.940 0.877 0.942
0.4 β 0 Bias 0.230 0.149 0.103 0.003 0.001 0.289 0.172 0.120 0.005 −0.001
SD 0.048 0.054 0.054 0.055 0.054 0.051 0.063 0.061 0.061 0.061
ASE 0.049 0.056 0.055 0.057 0.057 0.050 0.060 0.059 0.061 0.061
CP 0.003 0.262 0.524 0.929 0.952 0.000 0.234 0.453 0.935 0.950
β 1 Bias −0.161 −0.001 −0.010 −0.006 −0.001 −0.231 0.001 −0.015 −0.013 0.000
SD 0.039 0.061 0.055 0.047 0.049 0.038 0.074 0.061 0.049 0.054
ASE 0.037 0.061 0.054 0.048 0.050 0.036 0.070 0.059 0.050 0.056
CP 0.038 0.942 0.935 0.935 0.957 0.003 0.952 0.919 0.922 0.950

0.7 0.2 β 0 Bias 0.181 0.100 0.054 0.004 −0.002 0.242 0.127 0.069 0.021 0.003
SD 0.046 0.050 0.050 0.054 0.052 0.044 0.053 0.052 0.057 0.054
ASE 0.046 0.051 0.050 0.053 0.052 0.046 0.053 0.053 0.057 0.055
CP 0.040 0.498 0.802 0.942 0.942 0.003 0.323 0.762 0.942 0.960
β 1 Bias −0.160 0.002 −0.002 −0.010 0.001 −0.230 0.001 −0.007 −0.030 −0.001
SD 0.035 0.054 0.047 0.043 0.044 0.032 0.055 0.046 0.042 0.044
ASE 0.034 0.051 0.044 0.042 0.042 0.032 0.057 0.048 0.043 0.046
CP 0.018 0.928 0.938 0.940 0.960 0.000 0.960 0.960 0.887 0.943
0.4 β 0 Bias 0.226 0.148 0.078 −0.002 −0.002 0.293 0.177 0.093 0.006 0.003
SD 0.049 0.056 0.056 0.060 0.059 0.051 0.061 0.058 0.058 0.059
ASE 0.050 0.054 0.053 0.056 0.055 0.049 0.057 0.056 0.060 0.058
CP 0.018 0.235 0.678 0.927 0.939 0.000 0.175 0.603 0.939 0.942
β 1 Bias −0.158 −0.002 −0.007 −0.007 0.001 −0.234 −0.001 −0.012 −0.012 −0.002
SD 0.038 0.056 0.048 0.046 0.045 0.038 0.066 0.054 0.048 0.050
ASE 0.037 0.054 0.048 0.045 0.045 0.036 0.061 0.052 0.048 0.050
CP 0.041 0.937 0.942 0.934 0.947 0.000 0.934 0.929 0.924 0.939

Note: SD denotes the sample standard deviation of the estimates; ASE is the average of the estimated standard errors; CP represents the coverage probability of the 95% confidence intervals.