Table 2.
Numbers of subjects, odds ratiosa (ORs) and 95% confidence limits (CI) for mate intake in liters/day (LPD), cumulative mate consumption in liters/day-years (LPDY) and related variables. Data from the Uruguay and IARC Multinational Case-Control Studies.
| Uruguay Study | IARC Study | Pooled Data | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Cases | Controls | OR | 95% CI | Cases | Controls | OR | 95% CI | OR | 95% CI | |
| Never-drinkerb | 27 | 190 | 1.00 | 56 | 223 | 1.00 | 1.00 | |||
| Ever-drinker | 583 | 1,311 | 1.56 | (0.9,2.6) | 725 | 1,480 | 1.61 | (1.1,2.3) | 1.60 | (1.2,2.2) |
| Cumulative mate consumption (LPDY) | ||||||||||
| 1–29 | 101 | 340 | 1.29 | (0.8,2.2) | 248 | 675 | 1.38 | (0.9,2.1) | 1.34 | (1.0,1.8) |
| 30–49 | 133 | 319 | 1.58 | (0.9,2.7) | 167 | 389 | 1.37 | (0.9,2.1) | 1.45 | (1.0,2.0) |
| 50–69 | 178 | 334 | 1.95 | (1.1,3.3) | 134 | 223 | 2.01 | (1.3,3.1) | 1.99 | (1.4,2.8) |
| 70–99 | 67 | 178 | 1.12 | (0.6,2.0) | 82 | 109 | 2.54 | (1.5,4.2) | 1.64 | (1.1,2.4) |
| ≥100 | 106 | 157 | 1.89 | (1.1,3.3) | 101 | 92 | 3.60 | (2.2,6.0) | 2.53 | (1.8,3.6) |
| Pc | 0.08 | <0.01 | <0.01 | |||||||
| Mate intake (liters/day) | ||||||||||
| 0.1–1.0 | 149 | 455 | 1.41 | (0.8,2.4) | 318 | 861 | 1.28 | (0.9,1.9) | 1.33 | (1.0,1.8) |
| 1.0–1.9 | 299 | 661 | 1.58 | (1.0,2.6) | 264 | 481 | 1.85 | (1.2,2.8) | 1.71 | (1.3,2.3) |
| 2.0–2.9 | 104 | 169 | 1.82 | (1.0,3.2) | 103 | 108 | 3.14 | (1.9,5.4) | 2.38 | (1.7,3.4) |
| ≥3.0 | 33 | 43 | 1.46 | (0.7,3.0) | 47 | 38 | 4.69 | (2.5,8.8) | 2.77 | (1.7,4.4) |
| P | 0.37 | <0.01 | <0.01 | |||||||
| Temperature | ||||||||||
| Warm | 48 | 212 | 0.93 | (0.5,1.7) | 120 | 285 | 1.38 | (0.9,2.2) | 1.20 | (0.8,1.7) |
| Hot | 417 | 914 | 1.64 | (1.0,2.7) | 512 | 1085 | 1.53 | (1.0,2.2) | 1.61 | (1.2,2.2) |
| Very hot | 120 | 202 | 1.79 | (1.0,3.1) | 93 | 110 | 2.61 | (1.6,4.2) | 2.15 | (1.5,3.1) |
| P | <0.01 | <0.01 | <0.01 | |||||||
| Years since last mated | ||||||||||
| 0 | 523 | 1201 | 1.00 | 630 | 1303 | 1.00 | 1.00 | |||
| 1–4 | 37 | 50 | 1.50 | (0.9,2.5) | 44 | 70 | 1.41 | (0.9,2.2) | 1.45 | (1.0,2.0) |
| 5+ | 23 | 60 | 0.87 | (0.5,1.5) | 51 | 107 | 1.04 | (0.7,1.6) | 0.96 | (0.7,1.3) |
| Pd | 0.47 | 0.38 | 0.22 | |||||||
| Age 1st mated | ||||||||||
| <12 | 239 | 362 | 1.00 | 238 | 438 | 1.00 | 1.00 | |||
| 12–16 | 217 | 623 | 0.44 | (0.3,0.6) | 234 | 380 | 1.31 | (1.0,1.8) | 0.74 | (0.6,0.9) |
| ≥17 | 127 | 326 | 0.58 | (0.4,0.8) | 253 | 662 | 0.93 | (0.7,1.3) | 0.71 | (0.6,0.9) |
| P | <0.01 | 0.55 | <0.01 | |||||||
ORs from logistic regression for the mate consumption variable, adjusted by smoking (pack-years, cigarettes/day), alcohol consumption (drink-years, drinks/day), age, sex, sex by education and for Uruguay income and urban/rural residence. Pooled ORs further adjusted for study. Models included a sex-specific fixed offset variable for the Uruguay data to account for differential effects of mate consumption in urban, never alcohol consumers. Numbers of cases and controls differ slightly from Table 1 due to missing data.
Referent category, except where noted. Numbers of cases and controls vary due to missing data.
P-value for the score test of no trend.
ORs and P-values computed among mate drinkers only relative to the lowest category.