Table 3.
Predictors of time to hospital admission
| Univariate Analysis | Multivariable Analysis | |||
|---|---|---|---|---|
| Variable | Hazard Ratio [95% CI] | p-value | Hazard Ratio [95% CI] | p-value |
| MELD ≥ 15 | 2.97 [2.10–4.20] | < 0.001 | 2.39 [1.64–3.48] | < 0.001 |
| HCC | 2.86 [1.66–4.90] | < 0.001 | 2.43 [1.41–4.19] | 0.002 |
| Age ≥ 50 | 1.54 [1.02–2.34] | < 0.001 | 1.56 [1.01–2.41] | 0.05 |
| Admission during baseline year | 2.71 [1.93–3.81] | < 0.001 | 1.70 [1.17–2.48] | 0.006 |
| Follow up liver clinic visits per year (per one visit increase) | 1.01 [1.00–1.02] | 0.004 | 1.009 [1.00–1.02] | 0.05 |
| Unmarried | 1.58 [1.13–2.22] | 0.008 | 1.59 [1.12–2.25] | 0.05 |
| Congestive heart failure | 1.75 [1.11–2.76] | 0.02 | -- | -- |
| Lactulose or rifaximin | 1.64 [1.13–2.38] | 0.009 | -- | -- |
| SBP prophylaxis | 1.91 [1.16–3.13] | 0.01 | -- | -- |
| Diuretic | 2.20 [1.58–3.07] | < 0.001 | -- | -- |
| ED visit during baseline year | 3.75 [2.02–6.96] | < 0.001 | -- | -- |
| ICU admission during baseline year | 1.62 [0.91–2.86] | 0.10 | -- | -- |
| Ascites | 2.89 [2.01–4.16] | 0.04 | -- | -- |
| CCI (per one point increase) | 1.11 [1.06–1.16] | < 0.001 | -- | -- |
| NP or PA seen on at least half of visits | 1.63 [0.99–2.68] | 0.05 | -- | -- |
| Number of medications (per one medication increase) | 1.05 [1.01–1.10] | 0.02 | -- | -- |