Table 4.

Association between major haplotypes of Cdx1 and Cdx2 and BE (adjusted for age, sex and hernia)

Gene	Haplotype	Frequency	OR (95% CI)	P value
Cdx1	AGATG	0.29	1.00	---
	AAGGA	0.16	1.86 (0.95 – 3.62)	0.07
	GAGGA	0.13	2.27 (1.14 – 4.54)	0.02*
	GGATG	0.11	0.83 (0.36 – 1.91)	0.66
	GAGGG	0.10	1.41 (0.64 – 3.09)	0.39
	AAGGG	0.08	2.13 (0.86 – 5.26)	0.10
	AGATA	0.04	0.69 (0.16 – 3.00)	0.62
	GAATG	0.03	2.34 (0.75 – 7.24)	0.14
	GGATA	0.02	0.52 (0.05 – 5.25)	0.58
	AGGGG	0.02	1.07 (0.25 – 4.61)	0.93
Cdx2	CAGAT	0.33	1.00	---
	TGGAC	0.25	0.58 (0.35 – 0.95)	0.03*
	CGTGC	0.13	0.71 (0.38 – 1.35)	0.30
	TAGAT	0.12	0.52 (0.25 – 1.09)	0.08
	CATGC	0.09	0.61 (0.30 – 1.25)	0.18
	TGGAT	0.03	0.62 (0.22 – 1.74)	0.37
	CGGAC	0.03	0.44 (0.11 – 1.69)	0.23
	TGTGC	0.02	0.79 (0.13 – 4.64)	0.79

^*Significant P value without correction for multiple testing.