Skip to main content
. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Schizophr Res. 2013 Dec 7;152(1):111–116. doi: 10.1016/j.schres.2013.11.021

Figure 1. ZNF804A allelic specific expression in DLPFC.

Figure 1

TOP: The structure of the 3′ end of the ZNF804A gene is shown (drawn to scale; exons are represented by boxes, introns by horizontal lines). The two genotyped SNPs are listed, and their location is indicated by lines relative to the ZNF804 gene. Below the gene scheme, the three identified haplotypes are represented as horizontal lines, the thickness of which is proportional to the haplotype frequency. Risk alleles are indicated by uppercase letters. BOTTOM: Individual data points (grey dots) represent the A/T allele ratio at the expressed rs12476147 SNP. gDNA ratios, cDNA ratios, and cDNA ratios divided into rs1344706 homozygotes (hom) and rs1344706 heterozygotes (het) are shown. The mean value for each distribution is also indicated by a horizontal bar. cDNA allele ratios are significantly higher than gDNA allele ratios in the rs1344706 heterozygotes (p-value = 0.02). Moreover, there is a significant difference in cDNA allele ratios between homozygotes and heterozygotes for the rs1344706 SNP (p-value = 0.03).

HHS Vulnerability Disclosure