Table 1.
Subject demographic
Group | Mean ± SEM age (years) | Sex | Mean ± SEM PMI (h) | Median Braak Score |
---|---|---|---|---|
NC | 86.3 ± 1.4 | N=15; 4M, 11W | 2.8 ± 0.2 | I |
PCAD | 85.8 ± 1.7a | N=14; 3M, 11W | 2.8 ± 0.2 | Vc |
MCI | 91.0 ± 1.9a,b | N=7; 2M, 5W | 2.6 ± 0.2 | IVc |
LAD | 80.8 ± 1.4a | N=15; 7M, 8W | 3.6 ± 0.4 | VIc |
DC | 68.9 ± 4.8 | N=12; 7M, 5W | 3.5 ± 0.4 | IIc |
p < 0.05 compared to DC
p < 0.05 compared to LAD
p ≤ 0.05 compared to NC
NC = age –matched normal control; MCI = mild cognitive impairment; PCAD = preclinical Alzheimer’s disease; LAD = late-stage Alzheimer’s disease; DC = diseased control; PMI=postmortem interval;