Fig. 2.

Ethanol intake in mice on the test day of the intermittent access to ethanol (IA) procedure. Animals were pretreated with either ADX71441 (3, 10, 17 mg/kg, p.o.) or its vehicle (1 % CMC) before being given two-bottle choice and their alcohol and water consumption was monitored at 2, 4, and 24 h time points (n =12/group). Ethanol intake per unit of body weight (gram per kilogram; a), volume of ethanol (b), and water intake (ml; c) are portrayed over the time course of a test day. Each point represents the observed mean (+SEM). *p <0.05, **p <0.01 vs. vehicle