Fig. 1.
Cytokine/chemokine release from MO3.13 cells treated with various inhibitors at a 10 μM concentration or solvent control in the presence of B. burgdorferi (Bb, MOI 10:1). Supernatants from the mature oligodendrocytes were collected after 48 h and analyzed by a multiplex ELISA. Values represent mean +/− standard deviation for a representative experiment. Experiments were repeated 2-3 times. Statistical significance was evaluated for each condition compared to Bb + DMSO. * p < 0.05; ** p < 0.01; *** p < 0.001