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. Author manuscript; available in PMC: 2014 Mar 9.
Published in final edited form as: Cytokine. 2013 Apr 17;62(3):369–381. doi: 10.1016/j.cyto.2013.03.027

Fig. 4.

Fig. 4

Differential gene expression of RPE cells after 10 μg/ml AGE stimulation for 24 h. Fold changes (normalized to GADPH household gene) are compared between Agilent OligoMicroarray (black bars) and qRT-PCR (gray bars). Values are expressed as relative fold changes with respect to their corresponding (untreated) controls. Primers used for each gene product are shown in Table 3. All data shown demonstrated a >2.0-fold change and reached significance (p < 0.05). The largest upregulated fold changes were seen in CXCL11, RSAD2 and IFIT2. The greatest downregulated fold changes were seen in C8B, CALN1 and GARBG2. Data represent the mean ± SD of three independent experiments for both microarray and qRT-PCR. The Pearson’s correlation coefficient of the microarray data and the PCR for the genes shown in red and blue is 0.89 (p < 0.05).