Table 1.
The averaged values estimated using different kinetic models, across five ROIs in the gray matter in different brain regions from ten healthy subjects, along with the paired statistical comparisons between groups.
| model | CBF (mL/100g/min) | ATT (s) | T1,eff (s) | R2 of fit | AICc of fit | BIC of fit |
|---|---|---|---|---|---|---|
| 2p_1.2s | 57±16 | 1.5±0.3 | 1.2 | 0.76±0.13 | 310±15 | 310±15 |
| 2p_1.6s | 47±13 | 1.4±0.3 | 1.6 | 0.82±0.09 | 307±17 | 306±17 |
| 2p_2.0s | 42±11 | 1.4±0.3 | 2.0 | 0.82±0.08 | 307±17 | 306±17 |
| 3p | 46±14 | 1.4±0.3 | 1.9±0.4 | 0.84±0.08 | 312±18 | 311±18 |
| 4p | 44±13 | 1.4±0.3 | 0.84±0.08 | 319±19 | 315±18 | |
| 5p | 44±13 | 1.4±0.3 | 0.83±0.09 | 328±19 | 320±18 | |
| P values from paired t-test | ||||||
| (2p_1.2s, 2p_1.6s) | 1.6×10−26 | 3.2×10−32 | 7.8×10−9 | 1.3×10−4 | 6.9×10−5 | |
| (2p_1.6s, 2p_2.0s) | 1.7×10−27 | 3.9×10−29 | 0.18 | 0.81 | 0.97 | |
| (2p_2.0s, 3p) | 1.1×10−4 | 2.3×10−3 | 9.5×10−10 | 8.8×10−12 | 5.4×10−9 | |
| (3p, 4p) | 8.8×10−4 | 0.12 | 0.27 | 1.2×10−22 | 1.4×10−15 | |
| (4p, 5p) | 0.15 | 0.86 | 9.6×10−6 | 6.4×10−36 | 1.4×10−24 | |