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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Clin Cancer Res. 2014 Jan 7;20(5):1288–1297. doi: 10.1158/1078-0432.CCR-13-2611

Figure 2.

Figure 2

Histologic similarities between patients and corresponding tumorgrafts. (a) Representative H&E, Ki67, pan-CK, and CD45 expression in tumorgraft model PH063 shows conserved morphology, proliferation index by Ki67, and epithelial phenotype by pan-cytokeratin (40x). Scale bar = 100 μm. (b) Cytokeratin staining in tumorgraft and source patient pathology sections (PH122 shown) were selected and quantified using ImageJ software as described in the Methods section (20x). Scale bar = 200 μm. (c) The calculated non-epithelial tissue for eight tumorgraft models were plotted against that of the source patient.