Figure 6. Pre-transplant treatment with anti-LFA-1 mAb eliminates the survival deficit in grafts subjected to prolonged ischemia.
(A) Survival of complete MHC-mismatched A/J cardiac allografts (n = 4-5) subjected to 0.5 or 8 h cold ischemia in recipients treated with 200 μg control rat IgG or anti-LFA-1 mAb on days -1 and 0. (B) Grafts were recovered 48 h post-transplant, digested, and graft infiltrating cells were analyzed and quantified by antibody staining and flow cytometry. **p < 0.01