Table 3.

Nonlinear mixed modeling: peak or nadir of inflammatory markers during the first 30 days post-AuSCT

Inflammatory marker	Estimated peak or nadir (days from transplant)	95% CI	P
Markers with significant peak
IL-6	9.00	6.01 to 11.99	< 0.0001
CRP	13.46	9.28 to 17.64	< 0.0001
IL-10	18.01	13.43 to 22.59	< 0.0001
Markers with significant nadir
SIL-1RA	4.71	1.69 to 7.72	0.003
SIL-6R	8.16	5.40 to 10.93	< 0.0001
Markers with no significant peak or nadir
IL-8	0	−47.1 to 47.1	0.999
STNF-R1	1.01	−9.27 to 11.29	0.844
STNF-R2	2.40	−2.56 to 7.37	0.335
MCP-1	2.74	−0.04 to 5.52	0.054
TNF-α	3.00	−1.54 to 7.54	0.191
MIP-1α	6.00	0.54 to 11.46	0.032
SIL-1R2	6.04	−4.55 to 16.62	0.257
SIL-2RA	18.00	−38.31 to 74.31	0.524

Abbreviations: AuSCT, autologous hematopoietic stem cell transplant; CI, confidence interval.