Table 2.
Odds ratios (OR) and 95 % confidence intervals (CI) for HPV positivity associated with smoking, alcohol use and African American race
| Characteristics | HPV prevalence | |||||||
|---|---|---|---|---|---|---|---|---|
| No. of subjects | Oropharyngeal* | No. of subjects | Other | |||||
| % HPV+ | OR** | (95% CI) | % HPV+ | OR** | (95% CI) | |||
| Current smoking | ||||||||
| Yes | 43 | 37.2 | 1.00 | - | 184 | 22.8 | 1.00 | - |
| No | 38 | 65.8 | 3.25 | (1.30–8.08) | 104 | 23.1 | 1.01 | (0.57–1.80) |
| Alcohol use | ||||||||
| Ever | 65 | 44.6 | 1.00 | - | 215 | 21.4 | 1.00 | - |
| Never | 14 | 71.4 | 3.10 | (0.88–10.92) | 74 | 27.0 | 1.36 | (0.74–2.50) |
| Race | ||||||||
| Other | 45 | 71.1 | 1.00 | - | 179 | 22.9 | 1.00 | - |
| African American | 36 | 25.0 | 0.14 | (0.05–0.37) | 125 | 24.8 | 1.11 | (0.65–1.90) |
| Smoking -adjusted | 0.13 | (0.05–0.38) | Smoking -adjusted | 1.12 | (0.63–1.99) | |||
| Alcohol-adjusted | 0.16 | (0.06–0.46) | Alcohol-adjusted | 1.13 | (0.64–2.01) | |||
*
Oro-pharynx was defined by ICD-O 4 digit topology codes; C019–C020 (base and dorsal surface of tongue), C051 (soft palate)-C052
**
Smoking or alcohol adjusted ORs exclude subjects with current smoking or alcohol use unknown and include marital status at diagnosis as a covariate