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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Pharmacotherapy. 2014 Jan 13;34(3):265–271. doi: 10.1002/phar.1388

Table 1. Distribution of SLCO1B1 single nucleotide polymorphisms in 12 healthy volunteers.

Characteristic African American Caucasian Combined population
SLCO1B1c.388G→A (*1b)
GG (reference) 3 (50.0%) 1 (16.7%) 4 (33.3%)
GA 2 (33.3%) 5 (83.3%) 7 (58.3%)
AA 1 (16.7%) 0 (0%) 1 (8.3%)
Allelic frequency % 33.3% 41.6% 37.5%
P value* 0.4
SLCO1B1 rs4149032 (intron tSNP)
TT (reference) 2 (33.3%) 1 (16.7%) 3 (25.0%)
TC 2 (33.3%) 3 (50%) 5 (41.7%)
CC 2 (33.3%) 2 (33.3%) 4 (33.3%)
Allelic frequency % 50.0% 58.3% 54.2%
P value* 0.6
SLCO1B1 c.463C→A (*4)
CC (reference) 4 (66.7%) 2 (33.3%) 6 (50.0%)
CA 2 (33.3%) 4 (66.7%) 6 (50.0%)
AA 0 (0%) 0 (0%) 0 (0.0%)
Allelic frequency % 16.7% 33.3% 50.0.0%
P value* 0.2
SLCO1B1 c.521T→C (*5)
TT (reference) 5 (83.3%) 2 (33.3%) 7 (58.3%)
TC 0 (0.0%) 4 (66.7%) 4 (33.3%)
CC 1 (16.7%) 0 (0.0%) 1 (8.3%)
Allelic frequency % 8.3% 16.7% 25.0%
P value* 0.7
*

Chi square testing of Hardy-Weinberg equilibrium