Table 4.

Results of single SNP analysis and the age of initiation of tobacco (AOI) outcome. Column 1 = SNP/Locus, column 2 = number of contributing datasets for each locus, column 3 = number of total subjects with genotypic and phenotypic information, column 4 = summary Beta, column 5 = summary P-value, column 6 = Cochrane’s Q statistic P-value. Random effects versus a fixed effects model produce nearly identical betas and P-values

SNP/Locus	Number of contributing datasets (AOI)	Number of Subjects	Summary beta (SE)	Summary P-value	Cochrane’s Q Statistic P-value
Locus 1: rs16969968	15	12,662	0.007 (0.013)	0.588	0.261
Locus 2: rs578776	15	12,662	0.02 (0.014)	0.233	0.723
Locus 3: rs588765	12	10,269	− 0.019 (0.015)	0.198	0.084
rs1948	11	9,278	− 0.027 (0.016)	0.362	0.138
rs684513	5	2,821	0.023 (0.034)	0.507	0.531