Table 5.

Results of single SNP analysis and the age of onset of regular smoking (AOS) outcome. Column 1 = SNP/Locus, columns 2 = number of contributing datasets for each locus, column 3 = number of total subjects with genotypic and phenotypic information, column 4 = summary Beta, column 5 = summary P-value, column 6 = Cochrane’s Q statistic P-value. Significant summary P-values are indicated with bold. Random effects versus a fixed effects model produce nearly identical betas and P-values

SNP/Locus	Number of contributing datasets (AOS)	Number of Subjects	Summary Beta (SE)	Summary P-value	Cochrane’s Q Statistic P-value
Locus 1: rs16969968	39	55,317	0.0004 (0.004)	0.917	0.052
Locus 2: rs578776	38	54,796	0.02 (0.007)	0.004	0.601
Locus 3: rs588765	34	49,240	− 0.009 (0.008)	0.297	0.01
rs1948	24	28,970	0.023 (0.009)	0.018	0.772
rs684513	12	15,950	0.032 (0.013)	0.017	0.676