Fig. 15.

Morphologic characteristics and phenotypes of MEOP in 42 prematurely born infants ages 31 to 37 weeks PMA. Three CME phenotypes were observed in the patients: (A) single central; (B) Parafoveal (when cystoid structures were grouped around the foveal center as shown within the white encircled areas), and (C) multiple elongated cystoid structures when the parafoveal and central fovea contained cystoid structures. For the multiple elongated CME phenotype, severity was scored as mild (C) if the foveal pit was present; moderate (D) if the fovea was bulging but Photoreceptor layer (PRL) was not affected and severe (E) when the fovea and PRL had a bulging shape (white arrow). (F) Magnified SDOCT scan to show morphologic characteristics found in severe CME. White asterisk is located within a cystoid space. (From Maldonado RS, O’Connell R, Ascher SB, et al. Spectral-domain optical coherence tomographic assessment of severity of cystoid macular edema in retinopathy of prematurity. Arch Ophthalmol 2012;130(5):572; with permission.)