Table 1.
Margin positive rate and adjusted risk of margin positive for patients with surgically treated rectal and rectosigmoid adenocarcinoma 1998–2007 (n=85,190)
| Characteristics | Total | Proportion margin positive | Adjusted odds ratio | ||
|---|---|---|---|---|---|
| No. | Col % | Row % | OR | 95% CI | |
| Overall | 85,190 | 100% | 5.2 | - | - |
| Age of diagnosis | |||||
| 18–49 | 11,932 | 14 | 5.9 | 1 | Reference |
| 50–75 | 54,416 | 63.9 | 4.9 | 0.96 | 0.88–1.05 |
| 76–90 | 18,842 | 22.1 | 5.7 | 1.18 | 1.07–1.32 |
| Gender | |||||
| Female | 37,203 | 43.7 | 5.1 | 1 | Reference |
| Male | 47,987 | 56.3 | 5.3 | 1.07 | 1.01–1.15 |
| Race | |||||
| White | 75,134 | 88.2 | 5.1 | 1 | Reference |
| Black | 5,951 | 7.0 | 6.6 | 1.21 | 1.08–1.36 |
| Others | 4,105 | 4.8 | 5.6 | 1.04 | 0.90–1.19 |
| Year of diagnosis | |||||
| 1998–1999 | 15,683 | 18.4 | 4.7 | 1 | Reference |
| 2000–2001 | 16,504 | 19.4 | 4.3 | 0.92 | 0.83–1.03 |
| 2002–2003 | 17,234 | 20.2 | 5.0 | 1.06 | 0.95–1.17 |
| 2004–2005 | 18,120 | 21.3 | 5.8 | 1.23 | 1.11–1.36 |
| 2006–2007 | 17,649 | 20.7 | 6.1 | 1.31 | 1.19–1.45 |
| Insurance status | |||||
| Private insurance | 13,138 | 15.4 | 4.7 | 1 | Reference |
| Not insured | 2,254 | 2.6 | 8.5 | 1.54 | 1.29–1.84 |
| Government | 67,733 | 79.5 | 5.2 | 1.10 | 1.00–1.21 |
| Unknown | 2,065 | 2.4 | 5.6 | 1.15 | 0.93–1.42 |
| Median income quartile | |||||
| < $30,000 | 11,239 | 13.2 | 5.6 | 1 | Reference |
| $30,000 – $35,000 | 15,761 | 18.5 | 5.4 | 1.04 | 0.93–1.17 |
| $35,000 – $45,999 | 24,247 | 28.5 | 5.3 | 1.05 | 0.94–1.18 |
| $46,000 + | 33,943 | 39.8 | 4.9 | 0.99 | 0.87–1.13 |
| Proportion without high school degree by Zip code | |||||
| < 14% | 14,022 | 16.5 | 5.5 | 1 | Reference |
| 14% – 19.9% | 20,493 | 24.1 | 5.5 | 1.04 | 0.94–1.15 |
| 20% – 28.9% | 21,345 | 25.1 | 5.2 | 1.02 | 0.91–1.14 |
| 29% + | 29,330 | 34.4 | 4.9 | 1.00 | 0.88–1.13 |
| Population density of residence | |||||
| Metro area | 69,087 | 81.1 | 5.1 | 1 | Reference |
| Urban area | 12,879 | 15.1 | 5.5 | 1.02 | 0.93–1.11 |
| Rural area | 3,224 | 3.8 | 5.4 | 0.97 | 0.83–1.14 |
| Tumor location | |||||
| Rectosigmoid | 32,294 | 37.9 | 4.9 | 1 | Reference |
| Rectum | 52,896 | 62.1 | 5.4 | 1.19 | 1.11–1.27 |
| AJCC 6th tumor stage | |||||
| I | 26,978 | 31.7 | 1.3 | 1 | Reference |
| IIA | 22,748 | 26.7 | 3.9 | 2.90 | 2.55–3.30 |
| IIB | 1,988 | 2.3 | 23.6 | 21.80 | 18.74–25.36 |
| IIIA | 5,954 | 7 | 2.2 | 1.70 | 1.39–2.08 |
| IIIB | 14,747 | 17.3 | 7.7 | 5.93 | 5.24–6.71 |
| IIIC | 12,775 | 15 | 11.5 | 8.33 | 7.36–9.42 |
| Tumor size | |||||
| <10mm | 2,874 | 3.4 | 2.6 | 1 | Reference |
| 11–20mm | 8,178 | 9.6 | 2.9 | 0.92 | 0.70–1.20 |
| 21–998mm | 62,055 | 72.8 | 5.6 | 1.09 | 0.86–1.38 |
| Unknown | 12,083 | 14.2 | 5.3 | 1.30 | 1.01–1.66 |
| Histology type | |||||
| Adenocarcinoma | 78,580 | 92.2 | 4.7 | 1 | Reference |
| Signet ring | 586 | 0.7 | 22.4 | 2.49 | 2.02–3.07 |
| Mucinous | 6,024 | 7.1 | 9.6 | 1.51 | 1.38–1.67 |
| Tumor grade | |||||
| Well- and moderately differentiate | 68,940 | 80.9 | 4.5 | 1 | Reference |
| Poorly- and un- differentiate | 11,902 | 14 | 9.4 | 1.44 | 1.33–1.56 |
| Unknown | 4,348 | 5.1 | 4.7 | 0.95 | 0.82–1.11 |