Fig. 2. Effects of mesenchymal-specific knockout of ESET on osteoclasts.
a, TRAP-positive osteoclasts in the proximal tibias of wild-type (WT) and (exon 15&16)CKO/CKO mutants were counted and shown as the average number ± S.D. Asterisks indicate significance of the counts in knockout vs WT animals (*p=0.58 for 1 week-old and **p=0.61 for 1 month-old). b, Representative osteoblasts (purple) from one month-old proximal tibias of wild-type and (exon 15&16)CKO/CKO mutants are shown. Nuclei within the osteoclasts are detected by DAPI and merged with the TRAP-staining images. Genotypes are indicated on the side. Scale bar: 50 μm.
