Table 4.

Planned Outcomes of the Therapeutic Hypothermia After Pediatric Cardiac Arrest Trials

Primary outcome

VABS ≥ 70 at 12 mo post CA

Secondary outcomes

All cases

Survival at 1 2 mo following CA

Change in neurobehavioral function from pre-CA baseline to 1 2-mo measurement (delta VABS-I I)

Tertiary outcomes

Survivors only

Neuropsychological battery score at 1 2-mo evaluation

Neurologic abnormality scores at 1 2-mo evaluation (modified Pediatric Resuscitation after Cardiac Arrest Neurologii Outcome Measure pediatric stroke scale)

Safety outcomes

All-cause 28-d mortality

Prevalence of culture-proven infection within 7 d

Blood

Urine

Respiratory

Other

Blood product requirement within 7 d post CA

Arrhythmias within 7 d

VABS = Vineland Adaptive Behavior Scales, CA = cardiac arrest.