Table 2.
Pharmacodynamic parameters of LHD and MLHD in the pancreas at 48 h after topical use.
| Amylase (U/L) |
MDA (nmol/mg) |
SOD (U/mgprot) |
TNF-α
(pg/mL) |
IL-6 (pg/mL) |
IL-10 (pg/mL) |
Pathologic score | |
|---|---|---|---|---|---|---|---|
| Normal | 1504 ± 372 | 0.03 ± 0.01 | 4.2 ± 1.5 | 0.06 ± 0.02 | 0.09 ± 0.03 | 0.37 ± 0.01 | 0.22 ± 0.22 |
| AP model | 4339 ± 611* | 0.10 ± 0.03* | 2.2 ± 1.1* | 0.12 ± 0.05* | 0.16 ± 0.04* | 0.42 ± 0.04 | 5.63 ± 1.31* |
| LHD | 2971 ± 730# | 0.05 ± 0.02# | 5.5 ± 1.9# | 0.06 ± 0.01# | 0.09 ± 0.03# | 0.33 ± 0.06 | 5.53 ± 2.27 |
| MLHD | 2517 ± 244# | 0.06 ± 0.02# | 5.8 ± 2.1# | 0.06 ± 0.01# | 0.08 ± 0.02# | 0.34 ± 0.03 | 5.75 ± 2.04 |
Compared with normal, *P < 0.05; compared with AP, # P < 0.05.
MDA: malondialdehyde; SOD: superoxide dismutase.