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. Author manuscript; available in PMC: 2015 Mar 15.
Published in final edited form as: Cancer. 2013 Dec 10;120(6):799–807. doi: 10.1002/cncr.28484

Figure 4.

Figure 4

In vitro induction of ETV6-NTRK3 rearrangements by radiation exposure. (A) Distribution of the 131I dose in the monolayer of cells within a T25 flask generated by Kernel integration. (B) Induction of DSBs by ionizing radiation as evident by formation of gH2AX nuclear foci. (C) Identification of ETV6-NTRK3 rearrangements in human thyroid cells after exposure to 1 Gy of 131I or γ-radiation. (D) Frequency of specific types of ETV6-NTRK3 rearrangements induced in vitro by 131I and g-radiation.