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. Author manuscript; available in PMC: 2015 Mar 15.
Published in final edited form as: Cancer. 2013 Dec 10;120(6):799–807. doi: 10.1002/cncr.28484

Table 1.

131I dose and other exposure-related characteristics by mutation type in post-Chernobyl papillary thyroid cancer

Genetic Alteration N (%)* 131I dose,
mean (Gy)		 Age at exposure,
mean (yrs)		 Age at surgery,
mean (yrs)		 Latency,
mean (yrs)
BRAF 9 (14.5%) 0.27 10.2 27.0 16.8
RAS 6 (9.7%) 0.21 10.9 29.5 18.6
PAX8-PPARγ 2 (3%) 0.62 12.2 25.8 13.5
RET/PTC 22 (36%) 1.22 6.4 22.3 15.9
ETV6-NTRK3 9 (14.5%) 2.27 8.1 23.9 15.8
None 18 (29%) 1.71 7.9 24.6 16.7
Total 62 1.27 8.1 24.5 16.5
*

Four tumors had two mutations each: BRAF and NRAS, NRAS and PAX8-PPARγ, BRAF and ETV6-NTRK3, RET/PTC1 and ETV6-NTRK3.