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. Author manuscript; available in PMC: 2014 Mar 9.
Published in final edited form as: J Thromb Haemost. 2006 Jun;4(6):1218–1225. doi: 10.1111/j.1538-7836.2006.01901.x

Fig. 3.

Fig. 3

Whole blood clotting time (WBCT) and activated partial thromboplastin time (APTT) after injection of HDV-PEPCK/BDD-cFVIII/WPRE. Blood samples were measured periodically for WBCT and APTT as described in Materials and methods. (A) WBCT was monitored for the indicated time. Dog A received 1 × 1012 vp kg−1, and dogs B and C received 3 × 1012 vp kg−1. WBCT of dog B was measured for 2 years, and dog C for 79 days until terminal sacrifice. Normal WBCT = 8–12 min.