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. Author manuscript; available in PMC: 2014 Aug 1.

Published in final edited form as: J Inorg Biochem. 2013 Apr 19;125:40–49. doi: 10.1016/j.jinorgbio.2013.04.002

Table 1.

Domain-specific binding dissociation constants for CaM.

	K_d (µM)
Domain (Site)	Ca(II)	Pb(II)
^aND (I, II)	11.50±0.68	1.40±0.30
^bCD (III, IV)	2.04±0.02	^c0.73±0.10
CD (III, IV)	--	^d0.67±0.06
CD (Secondary)	--	1.93±0.32

^a

N-terminal domain

^b

C-terminal domain

^c

Direct titration

^d

Competitive titration with Ca(II)