Table 3. Improvement from Baseline According to Arm.

RBANS Index	Arm	Baseline Mean (SD)	Improvement at 4 months Mean (SD)	Model-Based 4-Month Change from Baseline Mean (95% CI)	P-value*
Primary Endpoints
Immediate Memory	Memory	96.3 (15.1)	5.2 (12.6)	3.7 (0.9-6.5)	0.012
	Weight Loss	95.9 (16.0)	4.4 (13.2)	2.5 (-0.5-5.6)	0.101
Delayed Memory	Memory	98.6 (14.7)	3.9 (11.3)	2.7 (0.0-5.4)	0.047
	Weight Loss	100.1 (13.6)	2.7 (10.4)	2.2 (-0.7-5.1)	0.122
Attention	Memory	93.8 (15.8)	4.3 (11.2)	4.3 (1.4-7.2)	0.007
	Weight Loss	92.8 (14.3)	3.1 (11.8)	3.2 (-0.1-6.4)	0.054
Secondary Endpoints
Visuospatial	Memory	99.6 (17.8)	-4.2 (16.0)	-3.1 (-6.9-0.7)	0.104
	Weight Loss	97.3 (18.6)	-4.3 (15.7)	-3.8 (-8.0-0.4)	0.070
Language	Memory	97.3 (11.4)	-1.5 (11.5)	-0.6 (-2.5-1.4)	0.561
	Weight Loss	96.0 (11.4)	-1.6 (11.7)	-0.5 (-2.7-1.7)	0.627

^*Testing the hypothesis that the improvement in RBANS subscale was significantly different from 0 within each arm after adjusting for baseline RBANS subscale, gender, and baseline BMI in a mixed model ANOVA.

Note: At 4 months N=105 for memory, n=106 for weight loss.