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. Author manuscript; available in PMC: 2014 Mar 9.
Published in final edited form as: Org Lett. 2010 Feb 19;12(4):892–895. doi: 10.1021/ol902969j

Table 2.

Variation of Reaction Conditionsa

graphic file with name nihms557339u3.jpg
entry mol % 10/mol % BzOH time d temp °C solvent % convn % ee
1 10/0 1 23 CDCl3 <5 ND
2 10/5 0.4 23 CDCl3 90 83
3 10/10 0.4 23 CDCl3 92 80
4 10/20 0.4 23 CDCl3 93 82
5 5/5 2 23 CDCl3 96 85
6 2/2 4 23 CDCl3 94 84
7 5/5 2 0 CDCl3 95 72
8 10/5 2 −20 CDCl3 94 55
9 5/5 1 45 CDCl3 91 84
10 5/5 2 23 C6D6 98 80
11 5/5 2 23 CH2Cl2 95 74
12 5/5 2 23 CH3CN 85 66
13 5/5 2 23 THF <5 ND
a

Conversion in all cases was determined by 1H NMR.