Skip to main content
. Author manuscript; available in PMC: 2015 Mar 14.
Published in final edited form as: Vaccine. 2013 Nov 16;32(13):1495–1500. doi: 10.1016/j.vaccine.2013.11.032

Figure 1.

Figure 1

Vaccination of cotton rats intranasally with anchorless F protein formulated with monophosphoryl lipid A (MPL) boosts protection against RSV infection. Cotton rats (n=5/group) were PBS-vaccinated (Mock) or vaccinated with 1.25 mg of baculovirus-expressed anchorless RSV F protein formulated with or without MPL (5 μg/rat) on day 0 and day 14. All animals were challenged on day 28 with RSV/A Long (105.5 pfu, i.n) and sacrificed on day 5 p.i. Log10 of RSV lung and nose titers are presented. Group marked with *represents p<0.01 when compared with the mock-vaccinated group.