Figure 1. Cell-surface adherence of C. albicans PK mutants.
(A) Adherence to silicone was measured using the Fluxion flow assay. The first bar on the graph represents wild-type level of adherence. Error bars represent standard deviation values. Mutants that filamented, had severe growth defects or aggregated were not assayed; these included homozygous insertion mutants for PBS2, GIN4, Orf19.1874, IME2, KIS1, SWE1, and CBK1. The wild-type strain is DAY286. (B) Adherence to silicone of wild type, tpk1Δ/tpk1Δ and tpk1Δ/tpk1Δ+TPK1Δ strains was measured using the Fluxion flow assay. ** denotes p=0.0011 for wild type versus tpk1Δ/tpk1Δ. The strains used were DAY185, SF1130, and SF1119.