Effect of aging on postischemic contractile function in sEH null mice. a, LVDP at baseline, at the end of ischemia, and at reperfusion (R10, R20, R30, and R40) in young and aged, WT and sEH null hearts. b, LVDP recovery at 40 min of reperfusion in young and aged, WT and sEH null hearts. c. Rate of contraction in young and aged, WT and sEH null hearts. d. Rate of relaxation in young and aged, WT and sEH null hearts. e. Heart rate in young and aged, WT and sEH null hearts. Values represent mean ± SEM; n=6–12 per group; *, p<0.05 vs. WT; #, p<0.05 vs. young animal of same genotype.