Age-related quantitative MRI changes in (A) fractional anisotropy (FA); (B) mean diffusivity (MD); (C) axial diffusivity (AD or λ||); (D) radial diffusivity (RD or λ⊥); (E) reconstructed fiber numbers using DTI; and (F) diameters of optic nerves in the young and old groups of rhesus monkeys. Young, the young group; Old, the old group; mean, mean value; SD, standard deviation; y, year.