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. 2013 Dec 20;122(3):269–276. doi: 10.1289/ehp.1307294

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Representative TEM photomicrographs showing retinal cellular injury of the ONL nucleolus (A–F) and photoreceptors (G–L) in control rats (A,G) and those exposed to white LED light (B–F, H–L) at day 9. Abbreviations: INL, inner nuclear layer; IS, inner segment; ONL, outer nuclear layer; OS, outer segment; RPE, retinal pigment epithelium. ONL nuclear deformations (arrows) were observed in (A) control ONL nucleus and as (B) nucleolus condensation, (C) karyolysis, (D,E) pyknosis, and (F) karyorrhexis. (G–L) Normal photoreceptor, IS, and OS from a control rat (G); photoreceptor deformations showing minor disruption (H,I); and IS disappearance followed by OS shrinkage and the formation of several small round shapes (J,K,L). For (A–F) and (I,J,L), bar = 1 μm; for (G,H,K), bar = 2 μm. Each photomicrograph is from a different sample.