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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Genes Immun. 2013 Nov 28;15(2):63–71. doi: 10.1038/gene.2013.60

Table 3. Association of TLR51846T>C with blood cytokine release induced by flagellin.

Cytokine Coefficient1 95% CI P
IL-6 −0.168 −0.280 – −0.056 0.003
IL-8 −0.180 −0.277 – −0.084 2.8 × 10−4
TNF-α −0.153 −0.252 – −0.054 0.003
IL-10 −0.151 −0.273 – −0.029 0.015
MCP-1 −0.048 −0.114 – 0.018 0.155
IL-1ra −0.038 −0.072 – −0.004 0.028
G-CSF −0.253 −0.400 – −0.107 7.7 × 10−4
IL-1β −0.169 −0.263 – −0.076 4.1 × 10−4
1

Linear regression coefficient for TLR51846T>C on log transformed cytokine levels induced by stimulation of whole blood from 300 healthy subjects with 500 ng/mL flagellin.