Table 7. Association of TLR5_1846T>C with blood cytokine release induced by flagellin independent of TLR5_1174C>T.

Cytokine	Coefficient1	95% CI	P
IL-6	−0.095	−0.226 – 0.035	0.152
IL-8	−0.110	−0.223 – 0.003	0.057
TNF-α	−0.080	−0.196 – 0.036	0.174
IL-10	−0.095	−0.237 – 0.047	0.188
MCP-1	−0.022	−0.100 – 0.056	0.575
IL-1ra	−0.032	−0.072 – 0.007	0.115
G-CSF	−0.205	−0.381 – −0.030	0.022
IL-1β	−0.120	−0.229 – −0.010	0.032

¹Linear regression coefficient for TLR5_1846T>C on log transformed cytokine levels induced by stimulation of whole blood from 269 healthy TLR5_1174CC subjects with 500 ng/mL flagellin.