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| Genotype | Adaptive Immune Responses |
|||
|---|---|---|---|---|
| Humoral |
Cellular |
|||
| Ab | Th-1 | Th-2 | Th-17 | |
| WT | + | + | +/− | + |
| MyD88−/− | + | − | + | − |
| TLR2−/− | + | − | + | − |
| TLR4−/− | + | − | +/− | − |
| IL-12−/− | + | − | + | − |
| IL-12Rβ1−/− | + | − | + | − |
| CD40−/− | − | − | − | − |
| CD86−/− | + | − | + | − |
| CD80/CD86−/− | − | − | − | − |
+ and − signify induction of immune response.
