Table 1. Expression of genes involved in Wnt signaling pathways in hCMEC/D3 cells.
| Name | Symbol | Expression level |
|---|---|---|
| Frizzled family receptor 1 | Fzd-1 | ++ |
| Frizzled family receptor 2 | Fzd-2 | ++ |
| Frizzled family receptor 3 | Fzd-3 | ND |
| Frizzled family receptor 4 | Fzd-4 | +++ |
| Frizzled family receptor 5 | Fzd-5 | ++ |
| Frizzled family receptor 6 | Fzd-6 | +++ |
| Frizzled family receptor 7 | Fzd-7 | + |
| Frizzled family receptor 8 | Fzd-8 | ++ |
| Dishevelled, dsh homolog 1 (Drosophila) | DVL-1 | ++ |
| Dishevelled, dsh homolog 2 (Drosophila) | DVL-2 | ++ |
| Dishevelled-associated activator of morphogenesis 1 | DAAM1 | +++ |
| Adenomatous polyposis coli | APC | ++ |
| Glycogen synthase kinase 3 beta | GSK3-b | +++ |
| Axin 1 | AXIN1 | ++ |
| Low-density lipoprotein receptor-related protein 5 | LRP-5 | ++ |
| Low-density lipoprotein receptor-related protein 6 | LRP-6 | ++ |
(+++: 20<Ct<25; ++: 25<Ct<30; +: 30<Ct<35; ND, not detectable Ct>35).